About this course
This course covers the concepts of:
- Mechanisms of axonal transport, neuronal cytoskeleton, neurite outgrowth, extracellular matrix, neurotrophic factors
- Mechanisms of synaptic transmission, vesicles, Snare’s, structure, synthesis and inactivation of neurotransmitters, neurotransmitterreceptors, signal transduction pathways; Pre and post synaptic signal modification
- Specific features of non-neuronal cells astrocytes, oligodendrocytes, microglia, Composition, synthesis and function of myelin, biochemistry and function of astrocytes and microglia; Pathobiochemistry of Alzheimer disease, prion diseases, leukodystrophies, polyglutamin diseases and multiple sclerosis
Learning outcomes
The aim of the module is to gain advanced knowledge about the structure of neurons and the molecular processes involved in neuronal communication. By the end of the module students should understand molecular and cell biology of axonal transport, synaptic transmission and its modulation and become familiar with the biochemistry of neurotransmitter synthesis, inactivation and degradation. The essential functions of non-neuronal cells will be covered. Students will be introduced in the pathobiochemistry of selected diseases. They should apply their knowledge while conducting basic biochemical experiments and analyse data obtained from the conducted experiments.
Prerequisites for participation
None
Necessary language skill
English
Interval at which Module/Course is offered
Every Winter Semester
Semester(s) in which the module takes place
Winter Semester
Course type
Lecture + Practical + Seminar
Course level
Masters
Course start date
09 Dec 2024
Course end date
17 Jan 2025
Involvement period
4 weeks during the Winter Semester
Teaching mode
Local
Local attendance
Required
Workload in ECTS
7.5
Graded
Yes
Person in charge of module
Prof. Dr. Thomas Becker
Local module ID
PM 3