About this course
Topics covered include:
- Mouse model of temporal lobe epilepsy
- Patch clamp analysis and single cell RT-PCR
- Analysis of gap junction-mediated astrocyte coupling by tracer diffusion assays
- Analysis of seizure activity by EEG and video monitoring
- Immunoblot analysis and Real-Time PCR
- Immunohistochemical staining and confocal microscopy
Learning outcomes
Students will receive hands-on experience with approaches and methods in epilepsy research. They will study changes in expression of key glial and neuronal proteins in human and experimental epilepsy. In addition, they will analyze epileptic seizure activity by EEG/behavioral monitoring in transgenic mice or mice treated with potential
novel anti-epileptic substances.
Prerequisites for participation
45 ECTS
Necessary language skill
English
Interval at which Module/Course is offered
Summer and Winter Semesters
Semester(s) in which the module takes place
Winter Semester
Course type
Practical + Seminar
Course level
Masters
Course start date
28 Oct 2024
Course end date
20 Dec 2024
Involvement period
8 weeks
Teaching mode
Local
Local attendance
Required
Workload in ECTS
15
Graded
Yes
Person in charge of module
Dr. Peter Bedner
Local module ID
WPP 23