About this course
This module is dedicated to understanding and investigating how small molecular modulators can be used to specifically target prominent metabolic pathways using the mouse as an experimental animal model. Attendees will be introduced to murine animal handling, murine primary adipocyte isolation and in vivo, ex vivo and in vitro pharmacological experimentation with the model system. The practical work will be supported by institute seminars covering, among other, signal transduction metabolism and pharmacology.
Learning outcomes
The following contents will be covered by the practical:
- Murine primary adipocyte isolation and culture
- Human adipocyte cell culture
- Pharmacological intervention of experimental model system
- Ex vivo and in vitro metabolic measurements (including oxygen consumption, energy expenditure, lipolysis, mitochondrial function, etc.)
- Data collection, analysis and interpretation
Prerequisites for participation
45 ECTS; successful participation at the Neuropharmacology module (WPM 13)
Necessary language skill
English
Interval at which Module/Course is offered
Summer and Winter Semesters
Semester(s) in which the module takes place
Winter Semester
Course type
Practical + Seminar
Course level
Masters
Course start date
06 Jan 2025
Course end date
28 Feb 2025
Involvement period
8 weeks
Teaching mode
Local
Local attendance
Required
Workload in ECTS
15
Graded
Yes
Person in charge of module
Prof. Alexander Pfeifer
Local module ID
WPP 49