This course covers the concepts of:

• Mechanisms of axonal transport, neuronal cytoskeleton, neurite outgrowth, extracellular matrix, neurotrophic factors
• Mechanisms of synaptic transmission, vesicles, Snare’s, structure, synthesis and inactivation of neurotransmitters, neurotransmitterreceptors, signal transduction pathways; Pre and post synaptic signal modification
• Specific features of non-neuronal cells astrocytes, oligodendrocytes, microglia, Composition, synthesis and function of myelin, biochemistry and function of astrocytes and microglia; Pathobiochemistry of Alzheimer disease, prion diseases, leukodystrophies, polyglutamin diseases and multiple sclerosis