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Brain Circuits

Karolinska Institutet
Neuroscience
About this course

Experimental neuroscience is key to progress in the understanding of how the brain functions. The experimental toolbox for studies in rodents is currently without comparison, allowing detailed investigation of how the brain is built and the function of brain circuits. Technological advances also make it possible to directly connect neurons and circuits to behaviour. 

In the Brain Circuits course, students will meet international and KI neuroscientists who have made significant contributions to the study and understanding of neuronal circuits and behaviour. The development and application of novel technologies and analysis (high-density electrophysiology and imaging of single-neuron activity, optogenetics, behavioural tracking, machine learning etc) will be covered, with a focus on advances using transgenic rodents. We have a strong emphasis on engaging junior neuroscientists in the course and on creating a network for future neuroscience leaders.

Learning outcomes

By the end of the course the student shall be able to:

  1. explain the structure and function of the main brain circuits
  2. describe the principles for excitatory and inhibitory networks
  3. including receptors and neurotransmitters, as well as the action of different chemical neuromodulators
  4. describe principles, use and readout of optogenetics and recording technologies
  5. describe principles and methods to define the structure (neuroanatomy) of brain circuits
  6. explain how dysfunctions of networks can manifest as neuropsychiatric disorders
  7. describe animal behavior tests probing specific networks and network functions
Prerequisites for participation

Knowledge of neuron function and brain anatomy is required.

SELECTION

Selection will be based on:  
1) the relevance of the course syllabus for the applicant’s doctoral project (according to written motivation). 

2) experience of neuroscience research (according to written motivation)

3) start date of doctoral studies (priority given to earlier start date). 

Necessary language skill
English
Interval at which Module/Course is offered
Monday - Friday 9.00-17.00
Semester(s) in which the module takes place
Autumn 2024
Course level
Doctoral
Course start date
14 Oct 2024
Course end date
18 Oct 2024
Apply between
Application start date
15 Apr 2024
-
Application end date
06 May 2024
Teaching mode
Local
Local attendance
2024-10-14 - 2024-10-18
Average workload
8 hours per week
Workload in ECTS
1.5
Graded
Yes
Availability of results
After module
Person in charge of module
Marie Carlén, Konstantinos Meletis, and Pierre Le Merre
Email address
pierre.le.merre@ki.se
Local module ID
C4F2624
Documents
Course syllabus (204.31 KB)