Impact of mitochondrial DNA mutations on neurodegenerative diseases
University of Bonn
Empirical & clinical neuroscience
About this course
Topics covered include:
- DNA isolation from human tissues
- Detection of mtDNA mutations in human samples by various PCR-based techniques
- Detection and quantification of multiple mtDNA deletion by single-molecule PCR
- mtDNA sequencing and deletion mapping
Learning outcomes
Students receive an introduction to mitochondrial genetics and learn basic techniques to investigate the relevance of mitochondrial mutations in neurodegenerative diseases.
Prerequisites for participation
45 ECTS
Necessary language skill
English
Semester(s) in which the module takes place
Winter Semester
Course type
Practical + Seminar
Course level
Masters
Course start date
28 Oct 2024
Course end date
20 Dec 2024
Involvement period
8 weeks
Teaching mode
Local
Local attendance
Required
Workload in ECTS
15
Graded
Yes
Person in charge of module
Prof. Dr. Wolfram S. Kunz
Local module ID
WPP 18