Brain function depends on a constant supply of glucose and oxygen from blood vessels. Efficient communication between neural cells and vessels is essential for correct brain function and relies on the selective transport of nutrients across the blood-brain barrier. Brains are particularly vulnerable to dysfunction of blood flow and loss of barrier properties, which can lead to dementia and neurodegenerative disease. The purpose of the course is to deepen the understanding of concepts underlying cerebrovascular development, cell signalling, imaging methods and vascular contributions to neurodegenerative diseases.
After the completed course, the students should be able to describe and understand the principles of molecular and cellular mechanisms responsible for neurovascular development, imaging and vascular contribution to neurological disease. The student should be able to use the acquired knowledge in their specific projects and areas of research.
Understanding of basic cell biology and molecular biology.
