Non-invasive brain stimulation (NIBS) fundamentals

General introduction to non-invasive brain stimulation (NIBS), and cover key concepts like circuits, plasticity, state-dependency and safety

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Course details
Non-credit course
University
Radboud University
Teacher
Lennart Verhagen
Category
Neurobiology
Dimension
Clinical neurotechnology
Level
Introductory
Includes
  • Video Lectures
  • Assignments

 

The goal of this course is to provide a general introduction to non-invasive brain stimulation (NIBS), and cover key concepts like circuits, plasticity, state-dependency and safety. In addition, the key cornerstones of safety in NIBS research will be discussed here. Knowledge of these concepts is essential for (safely) designing and implementing any valid NIBS study.

Course Features
Overview of non-invasive brain stimulation (NIBS) techniques

Lessons

Number of lessons: 7
  •  
    Introduction to NIBS: NIBS in a nutshell
    Lennart Verhagen

    Overview of non-invasive brain stimulation (NIBS) techniques: The different NIBS techniques are introduced: transcranial magnetic stimulation (TMS), transcranial electric stimulation (tES), and transcranial…

  •  
    Why intervention matters
    Lennart Verhagen

    This lecture uses examples from the literature to demonstrate how NIBS can be used to make causal inferences, and for therapeutic interventions. Additionally, the importance of choosing optimal brain targets, and…

  •  
    Circuit intervention
    Lennart Verhagen

    The effects of stimulating a focal brain target, depend not only on the state of the target but also on the state of the circuits or networks to which the target belongs. Conversely, the effects of stimulating a…

  •  
    Brain plasticity
    Lennart Verhagen

    This lecture introduces the principles of plasticity including spike-timing-dependent, dose-dependent, and homeostatic plasticity, and discusses the neural underpinnings of plasticity. Finally, examples from the…

  •  
    State dependency
    Lennart Verhagen

    This lecture uses examples from the literature to demonstrate how the underlying brain state at the time of stimulation influences NIBS effects. Different factors that influence brain state including anaesthesia,…

  •  
    Safety
    Lennart Verhagen

    This lecture lays out the framework for discussing NIBS effects in the context of safety. Specifically, the primary (intended) and secondary effects are distinguished, with a…

  •  
    Screening questionnaire
    Lennart Verhagen

    This lecture discusses each item on a screening questionnaire used for assessing whether participants are eligible for negligible risk NIBS experiments. The goal of this lecture is…

Lessons in TrainingSpace

Number of lessons: 2
  •  
    A Multiscale Approach to Brain Disorders
    Krembil Centre for Neuroinformatics
    This lesson is a general overview of overarching concepts in neuroinformatics research, with a particular focus on clinical approaches to defining, measuring, studying, diagnosing, and treating various brain disorders. Also described are the complex…
  •  
    Problems and Opportunities in the Diagnosis and Treatment of Major Depression
    Krembil Centre for Neuroinformatics
    The state of the field regarding the diagnosis and treatment of major depressive disorder (MDD) is discussed. Current challenges and opportunities facing the research and clinical communities are outlined, including appropriate quantitative and…