The purpose of this course is to enable doctoral students and other participants to gain an understanding of the major neuroinflammatory diseases and the key players involved, including the interaction between the central nervous and immune systems. An additional purpose is that those who participate in the course learn to understand critical aspects of creating and using experimental systems to model neuroinflammatory diseases.

The course is offered full time, Monday-Friday, 9:00-17:00 at the Center for Molecular Medicine (CMM) on Karolinska University Hospital, campus Solna, building L8, lecture hall and seminar rooms.

This course is given jointly by the doctoral programmes Allergy, immunology and inflammation (Aii) and Neuroscience (Neuro

Developmental biology lies at the heart of an effort to understanding complex biological systems. By studying how neural circuits are assembled we can extrapolate key aspects of their function as well as devise strategies for their repair. This course is given to deepen the understanding of how molecular and cellular mechanisms underlie neurobiological function and to widen the horizon of students within the strong Karolinska neuroscience community.

The course is given in collaboration with the Master's Programme in Biomedicine.

This is a full time course given in person at Biomedicum, Campus Solna.

Link to course evaluation

https://survey.ki.se/Report/5biVHpOK5wg

Experimental neuroscience is key to progress in the understanding of how the brain functions. The experimental toolbox for studies in rodents is currently without comparison, allowing detailed investigation of how the brain is built and the function of brain circuits. Technological advances also make it possible to directly connect neurons and circuits to behaviour. 

In the Brain Circuits course, students will meet international and KI neuroscientists who have made significant contributions to the study and understanding of neuronal circuits and behaviour. The development and application of novel technologies and analysis (high-density electrophysiology and imaging of single-neuron activity, optogenetics, behavioural tracking, machine learning etc) will be covered, with a focus on advances using transgenic rodents. We have a strong emphasis on engaging junior neuroscientists in the course and on creating a network for future neuroscience leaders.

This course is given in collaboration with the Master's Programme in Biomedicine.

The course is designed to provide students and researchers with a solid understanding of functional Near-Infrared Spectroscopy (fNIRS) as a relatively new tool to measure brain activity and will emphasize both theoretical knowledge and practical skills of fNIRS. The students will gain expertise in the underlying principles of fNIRS, its instrumentation, and various analytical approaches. The primary goal is to empower students with the knowledge of this additional neuroimaging tool to design and execute advanced experiments, interpret fNIRS data effectively, and contribute to cutting-edge research in neuroscience and related fields.

The course overlaps with the course Imaging in neuroscience: with a focus on fNIRS, offered at Karolinska Institute and The Swedish School of Sport and Health Sciences (GIH). The sessions will be a mix of in person and virtual meetings with practical sessions held at uMOVE - Gävlegatan 55, Solna and at the BMC-lab at GIH – Lidingövägen 1, Stockholm

The purpose of the course is for participants to gain knowledge concerning genetics, molecular mechanisms as well as clinical features and treatment strategies of neurodegenerative disorders.

This course is given in collaboration with the Master's Programme in Biomedicine.

The course is designed to provide students and researchers with a solid understanding of functional Near-Infrared Spectroscopy (fNIRS) as a relatively new tool to measure brain activity and will emphasize both theoretical knowledge and practical skills of fNIRS. The students will gain expertise in the underlying principles of fNIRS, its instrumentation, and various analytical approaches. The primary goal is to empower students with the knowledge of this additional neuroimaging tool to design and execute advanced experiments, interpret fNIRS data effectively, and contribute to cutting-edge research in neuroscience and related fields.

The main purpose of the course is to provide the students with a solid understanding of the tools available to analyze brain structural data measured with structural magnetic resonance imaging (sMRI). The students will develop the ability to critically review results provided by different methods, to select the most adequate tools and experimental designs to answer different questions and to compare their relative advantages.

Participants receive basic and advanced knowledge of neurophysiology and information about relevant methods (e.g. evoked potentials, extra- / intracellular, patch clamp recordings). Properties of ion channels as well as cellular and network
properties of selected model systems (leech, goldfish, hippocampus) will be discussed.

This course is a basic course on advanced fluorescence microscopy imaging and correlation spectroscopy techniques for quantitative characterization of molecular transport and interactions in live cells. The purpose of the course is to give an introduction of the underlying physicochemical principles, hands-on training and an overview of applications of these specialized techniques in biomedical research. At the end of the course, the student will have hands-on experience with live-cell imaging and specialized fluorescence microscopy and correlation spectroscopy techniques. The course is suitable for doctoral students lacking training in mathematics, physics, or optical engineering who want to apply these techniques in their research.

The course reviews central concepts and topical research in stress, sleep and health. In particular, it is focused on how acute stress, chronic stress, diurnal rhythm and sleep problems affect and interact physiological systems such as the immune system, the endocrine system, cognitive processes and possible consequences for health. The course encompasses neuroscientific and other biological perspectives, and describes interventions to improve stress- and sleep related symptoms. Theoretical models and methods to understand and study stress- and sleep related processes will be applied. 

The course will be provided fully online, partly via Zoom but also taking advantage of recent digital tools such as Gather; and using Canvas as the learning platform in-between in-class sessions.

Our MATLAB-based comprehensive course is designed to equip you with the essential knowledge and practical skills to delve into biomedical image processing, specifically tailored for biological/medical and neuroimaging applications using MATLAB.

Selection will be based on:
1) the relevance of the course syllabus for the applicant's doctoral project (according to written motivation),
2) start date of doctoral studies (priority given to earlier start date)

The course provides a deeper understanding of neurodegenerative disorders from a basic to a clinical perspective. It consist of a combination of lectures, lab demonstrations and group dicussions led by experts in the field. It covers cellular and molecular pathophysiological mechanisms of neurodegenerative disorders and the mechanisms of current and/or possible future treatments. We will discuss similarities and differences between the different neurodegenerative diseases. The students will also be introduced to some powerful techniques that can be used for studying neurodegeneration, subcellular localization, and omics approaches. We will discuss advantages and drawbacks of important methods and models for studying mechanisms behind neurodegenerative disorders

SELECTION

Selection will be based on:  
1) the relevance of the course syllabus for the applicant’s doctoral project (according to written motivation). 
2) start date of doctoral studies (priority given to earlier start date).