The course content lean on Design thinking ideology and methodology that inform research as well as developmental work and form a practice-based foundation for innovation aimed to meet the needs of societal and scientific environments. As a student, you work  individually from your own research perspective, and get helpful insights for future research.  

The course apply a problem-oriented teaching and learning style,  with a pedagogy that enables students to take active responsibility for individual and also group learning in a multi-disciplinary context.

Progress in medical innovation stands as a catalyst for worldwide economic growth. Whether within pharmaceuticals, medical devices, biotechnology, information technology, or a fusion of these advancements, the potential advantages extend significantly to private businesses and societal well-being. However, due to long development times and rigorous regulations, these innovative concepts require a lot of financing to establish their presence in the market. Consequently, assessing the value of novel medical innovations remains crucial. The primary objective of this course is to empower researchers with the proficient capability to effectively assess the worth of emerging technologies or processes within the medical industry.

The "Clinical Research in Child and Adolescent Psychiatry: Methods and Practice" course aims to cover a range of methodological factors in clinical trials on youths with psychiatric disorders, including psychiatric assessment and psychological as well as pharmacological treatment. The course will provide broad as well as in-depth knowledge about methodological and practical aspects of clinical psychiatric research focusing on children and adolescents. The course also addresses good clinical practice principles and Swedish and international rules and regulations relevant to clinical research involving young individuals.

Dive into the cutting-edge world of nuclear medicine with this comprehensive course that blends theory and hands-on practice. In this one-week course, you will gain invaluable knowledge and skills at the forefront of medical imaging and targeted radiopharmaceutical therapies.

This course offers a unique opportunity to:

• Master the fundamentals of radiation physics and biology
• Explore state-of-the-art diagnostic and therapeutic applications in oncology and neurology
• Gain practical experience handling radiopharmaceuticals in a laboratory setting
• Understand the latest developments in personalised medicine using radioactive tracers

Upon completing the course, you will be allowed to handle radiopharmaceuticals and open radioactive sources at Karolinska Institute and Karolinska University Hospital.

The course is designed to provide students and researchers with a solid understanding of functional Near-Infrared Spectroscopy (fNIRS) as a relatively new tool to measure brain activity and will emphasize both theoretical knowledge and practical skills of fNIRS. The students will gain expertise in the underlying principles of fNIRS, its instrumentation, and various analytical approaches. The primary goal is to empower students with the knowledge of this additional neuroimaging tool to design and execute advanced experiments, interpret fNIRS data effectively, and contribute to cutting-edge research in neuroscience and related fields.

The main purpose of the course is to provide the students with a solid understanding of the tools available to analyze brain structural data measured with structural magnetic resonance imaging (sMRI). The students will develop the ability to critically review results provided by different methods, to select the most adequate tools and experimental designs to answer different questions and to compare their relative advantages.

The course will introduce neuropsychological assessment in an aging population, focusing on age-related cognitive changes and their neural correlates. An additional purpose is to increase understanding of cognitive aging and how to differentiate between non-pathological cognitive aging and early signs of pathology. After the course, you will be able to define and describe common neuropsychological concepts and measurement techniques and demonstrate an overall understanding of neuropsychological investigation methodology and cognitive diagnostics in aging. The course will give you an increased understanding of cognitive aging and the complexity of differentiating between “normal” and early-stage pathological aging.

This course will provide curious students with an overview of the field of nervous system injury and possibilities for repair. We will focus on the cellular pathobiology but have a translational outlook and integrate the clinical perspective. The student will after the course know the basic concepts and recognise relevant research questions in the field. Hence, the student have aquired up to date information and understanding of the problems and possibilities for repairing an injured central or peripheral nervous system. 

The course is aimed for you who want to get an understanding of the principles of PET, the methodology used for neuroreceptor imaging and quantification, as well as to get an insight in important research ongoing in the field and in the clinical applications of PET.

This course has the main general purpose of connecting two topics, or disease types, which are generally known by the scientific community to be completely distant from each other, such as Infections of the Central Nervous System (Neuro-Infections) and neurodegenerative diseases/dementia.  

Students should gain knowledge on the common neuroinflammatory processes and molecular mechanisms of neuronal damage that are common between neurodegenerative diseases and Central Nervous System infections. These learning outcomes reflect the purpose of the course, which is of shedding light into the interplay between dementia/neurodegenerative disease and infections and try to understand the molecular biology that connects these two types of brain disease. 

This course provides a solid ground in neuroscience, including cellular neuroscience, sensory and motor functions, and higher brain functions. It is intended for those lacking a basic neuroscience education. It runs in parallel with the Neuroscince course of the Bachelors programme in biomedicine. The course does not give regular course credits for doctoral students, but can be used to cover the demand of a grounding course in human physiology/pathology.

The purpose of the course is to give doctoral students a broad knowledge of Alzheimer's disease, covering cellular
mechanisms as well as clinical features and diagnosis. Experts in the field are invited to give the lectures securing
communication of up-to-date knowledge about the disease. Students will also get the opportunity to obtain deeper
knowledge on specific sub-topics during the planned group assignments. The second part will provide pratical
knowledge about brain development, brain anatomy and connectivty and AD and dementia neuropathologies.

This course aims to introduce students to health care organization and management, and how this affects public health. There is a special focus on the opportunities offered by digitization and how these can be utilized in quality and improvement work.

The purpose of the course is to introduce the topic of artificial intelligence (AI) in mental healthcare focused on theoretical development, ethics and practical application informed by a scientific approach.

This course provides students with in-depth knowledge in the field of digital health from an entrepreneurship perspective. Domains of digital health, needs-based innovation including prototyping, usability and testing as well as data management, intellectual property, reimbursement, business models, ethics and future trends will be discussed and analyzed.

This course is a basic course on advanced fluorescence microscopy imaging and correlation spectroscopy techniques for quantitative characterization of molecular transport and interactions in live cells. The purpose of the course is to give an introduction of the underlying physicochemical principles, hands-on training and an overview of applications of these specialized techniques in biomedical research. At the end of the course, the student will have hands-on experience with live-cell imaging and specialized fluorescence microscopy and correlation spectroscopy techniques. The course is suitable for doctoral students lacking training in mathematics, physics, or optical engineering who want to apply these techniques in their research.

The course aims to introduce students to human sensory perception with a focus on clinical utility and research. The neurological and evolutionary principles underlying vision, hearing, smell, taste, touch, and additional methods of perception will be covered.

The course will introduce the historical and evolutionary context for our senses, so as to provide an understanding for why humans operate and behave the way we do. Beyond the traditional five senses of vision, hearing, taste, smell, and touch, we will discuss several other sensory modalities available to humans, including the vestibular system. The neurological principles guiding the integration of these senses will be outlined, with special reference to subconscious and conscious decision-making. These systems will then be tested through a series of practical experiments, giving students a chance to reflect on blind-spots in human perception and how to implement these in a scientific and clinical setting. Finally, common sensory pathologies will be discussed.

Why doesn't the mammalian central nervous system (CNS) regenerate while many other tissues do? Which cutting-edge technologies and models are most effective for studying CNS repair? What regenerative strategies can be designed to rebuild such a complex tissue? Led by renowned experts and featuring distinguished international speakers, this course will delve into the intricacies of how the CNS responds to injury at a cellular and molecular level, as well as the most advanced research into regenerative therapies ranging from stem cell-based to gene therapies. The curriculum spans from fundamental research to preclinical development, with a particular focus on state-of-the-art approaches for studying CNS injury, degeneration, and repair.

Selection will be based on:
1) the relevance of the course syllabus for the applicant's doctoral project (according to written motivation),
2) start date of doctoral studies (priority given to earlier start date)

Our MATLAB-based comprehensive course is designed to equip you with the essential knowledge and practical skills to delve into biomedical image processing, specifically tailored for biological/medical and neuroimaging applications using MATLAB.

Selection will be based on:
1) the relevance of the course syllabus for the applicant's doctoral project (according to written motivation),
2) start date of doctoral studies (priority given to earlier start date)

The course provides a deeper understanding of neurodegenerative disorders from a basic to a clinical perspective. It consist of a combination of lectures, lab demonstrations and group dicussions led by experts in the field. It covers cellular and molecular pathophysiological mechanisms of neurodegenerative disorders and the mechanisms of current and/or possible future treatments. We will discuss similarities and differences between the different neurodegenerative diseases. The students will also be introduced to some powerful techniques that can be used for studying neurodegeneration, subcellular localization, and omics approaches. We will discuss advantages and drawbacks of important methods and models for studying mechanisms behind neurodegenerative disorders

SELECTION

Selection will be based on:  
1) the relevance of the course syllabus for the applicant’s doctoral project (according to written motivation). 
2) start date of doctoral studies (priority given to earlier start date). 

The course consists of theoretical sessions and practical work related to decision-making, memory formation and emotion. It will also include the neuroanatomy related to these functions using both MRI and human brains. The participants will be actively involved in group work dealing with practical and theoretical aspects of cognitive neuroanatomy.

Selection will be based on:
1) the relevance of the course syllabus for the applicant's doctoral project (according to written motivation),
2) start date of doctoral studies (priority given to earlier start date)

Developmental biology lies at the heart of an effort to understanding complex biological systems. By studying how neural circuits are assembled we can extrapolate key aspects of their function as well as devise strategies for their repair. This course is given to deepen the understanding of how molecular and cellular mechanisms underlie neurobiological function and to widen the horizon of students within the strong Karolinska neuroscience community.

Contents of the course: The course will cover the main steps of development from neural stem cells to mature circuits, including the patterning of the neural plate and thus the origin of cell types, the interplay between intrinsic and extrinsic factors, gene regulation including epigenetics, neuro-glia interactions and the role of network activity in shaping the final circuits. Different molecular and tracing technologies, and model organisms will be covered. An important aspect of the course regards molecular technologies for labeling, transcriptional analysis, and genetic manipulation of defined neural populations. Connections between aberrant developmental processes and neurodevelopmental and neurological disorders will be discussed.

Course director

The course is given by four course-leaders: Gonçalo Castelo-Branco, Jens Hjerling-Leffler and Ulrika Marklund all at MBB and François Lallemend at Dept of Neuroscience.

The purpose of the course is for participants to gain knowledge concerning genetics, molecular mechanisms as well as clinical features and treatment strategies of neurodegenerative disorders.

SELECTION

Selection will be based on:  
1) the relevance of the course syllabus for the applicant’s doctoral project (according to written motivation). 
2) start date of doctoral studies (priority given to earlier start date). 

Experimental neuroscience is key to progress in the understanding of how the brain functions. The experimental toolbox for studies in rodents is currently without comparison, allowing detailed investigation of how the brain is built and the function of brain circuits. Technological advances also make it possible to directly connect neurons and circuits to behaviour. 

In the Brain Circuits course, students will meet international and KI neuroscientists who have made significant contributions to the study and understanding of neuronal circuits and behaviour. The development and application of novel technologies and analysis (high-density electrophysiology and imaging of single-neuron activity, optogenetics, behavioural tracking, machine learning etc) will be covered, with a focus on advances using transgenic rodents. We have a strong emphasis on engaging junior neuroscientists in the course and on creating a network for future neuroscience leaders.