Brain Recovery

Brain Recovery: Understanding Mechanisms and Therapeutic Strategies for Stroke and TBI Rehabilitation

Course details
Non-credit course
University
Universitatea de Medicină și Farmacie din Cluj-Napoca
Institution
Doctoral School of Neuroscience
Teacher
Prof. Dr. Dafin Fior Mureșanu
Category
Clinical neuroscience
Dimension
Empirical neuroscience & Clinical neuroscience
Level
Expert

Understanding how the brain repairs itself after injury represents one of the most fascinating challenges in neuroscience. The Brain Recoverycourse takes participants on a journey through the biological mechanisms and clinical approaches that drive recovery after stroke and traumatic brain injury (TBI). 

Through five expert-led lectures by Prof. Dr Dafin Fior Mureșanu, participants will gain insight into the mechanisms of endogenous neuroprotection and neuroplasticity, the role of microcirculation in brain repair and the impact of multimodal neurotrophic and pharmacological interventions. The course also covers important findings from landmark clinical studies such as the CARS and CAPTAIN trials and introduces the EAN–EFNR guideline for early motor neurorehabilitation after ischaemic stroke.

By the end of the course, participants will have a clearer understanding of how different therapeutic strategies and advanced assessments can improve outcomes for patients, linking scientific research to clinical practice in meaningful ways.

This course is offered in collaboration with the Doctoral School of Neuroscience, “Iuliu Hațieganu” University of Medicine and Pharmacy, Cluj-Napoca.

Course Features
Explain the structural and functional levels of brain damage and recovery mechanisms following stroke and TBI.
Describe the concepts of endogenous neuromodulation, neuroprotection and neuroplasticity.
Discuss the role of neurotrophic factors and multimodal pharmacological interventions in promoting brain recovery.
Summarize the design, methods and clinical implications of the CARS and CAPTAIN trials.
Evaluate evidence-based approaches and guideline recommendations for early
Reflect on how emerging neurotechnologies and multidimensional assessments are reshaping the future of neurorecovery research.

Lessons

Number of lessons: 5
  •  
    CAPTAIN Trials (I and II) – a new horizon in TBI Treatment
    Prof. Dr. Dafin Fior Mureșanu

    Traumatic Brain Injury (TBI) remains one of the major global health challenges, representing a leading cause of disability and death. In 2016 alone, approximately 27 million new cases of TBI contributed to the global burden of disease. This…

  •  
    Advances and updates in neurorecovery after stroke – new EAN-EFNR guideline
    Prof. Dr. Dafin Fior Mureșanu

    The EAN–EFNR guideline provides updated, evidence-based recommendations on pharmacological support during early motor rehabilitation after acute ischemic stroke. Using the GRADE methodology, it integrates data from multiple meta-analyses…

  •  
    Challenges and opportunities in stroke recovery
    Prof. Dr. Dafin Fior Mureșanu

    Stroke remains a leading cause of death and disability worldwide. Brain injury affects all structural and functional levels, from cellular and molecular to circuit and network organisation, triggering endogenous defence responses that…

  •  
    New Vistas in Stroke Recovery
    Prof. Dr. Dafin Fior Mureșanu

    Recent clinical trials have confirmed the positive effects of neurotrophic factors on neurological recovery after acute ischemic stroke. The CARS study evaluated neurotrophic factor treatment combined with standardized rehabilitation.…

  •  
    Microcirculation and stroke
    Prof. Dr. Dafin Fior Mureșanu

    Revascularisation therapies have transformed the management of acute ischaemic stroke. Fibrinolytic agents (rtPA) and endovascular thrombectomy are now standard treatments, aiming to restore cerebral blood flow and limit damage within the…