Biostatistical Analysis / Methods
Comprehensive overview of key statistical methods used in biomedical research, including multiple comparisons, correlations, and survival analysis
This course offers a comprehensive overview of key statistical methods used in biomedical research, including multiple comparisons, correlations, and survival analysis. Students will learn to select and apply appropriate statistical tests to analyze data and determine the impact of new methodologies. Key topics include data sampling, measures of central tendency and dispersion, hypothesis testing, regression models, non-parametric tests, and survival analysis techniques. Through eleven expert-led lectures by Prof. Dr. Esin Ozturk-Isik, participants will gain insight into the mathematical logic governing inferential statistics and the practical application of these tools in clinical settings. The course also covers the transition from summarizing simple biological distributions to complex analyses involving multiple treatment groups, categorical data rates, and the critical assessment of statistical power. By the end of the course, participants will have a clearer understanding of how to design robust experiments, avoid common pitfalls like alpha error inflation, and interpret results through both p-values and confidence intervals to distinguish between statistical significance and clinical relevance.
This course collection is offered as part of the TACTIX project in collaboration with Boğaziçi University, Amsterdam UMC and Fraunhofer MEVIS.
Target Audience: MSc and PhD students interested in analyzing clinical data for research purposes.
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Lessons
Number of lessons: 6-
Esin Ozturk-Isik
This lecture provides an essential introduction to biostatistics, focusing on how to correctly describe and summarize biological data. It addresses the common misuse of statistics in medical literature and introduces the…
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Esin Ozturk-Isik
This lecture introduces Analysis of Variance (ANOVA), a parametric statistical method used to test hypotheses across three or more treatment groups. The session explains the logic behind partitioning variance—comparing variability…
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Esin Ozturk-Isik
This lecture focuses on the Student’s t-test, the most common statistical procedure for comparing the means of two independent groups. It highlights a frequent error in medical research: the misuse of multiple t-tests to compare…
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Esin Ozturk-Isik
This lecture transitions from interval data to nominal data, where outcomes are categorical rather than measured on a scale (e.g., dead vs. alive, treatment vs. placebo). It introduces the Z-test for comparing two proportions and…
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Esin Ozturk-Isik
This lecture explores the critical concepts of statistical power and sample size. It addresses the common "not significant" dilemma: does a lack of significance mean there truly is no treatment effect, or was the study simply too…
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Esin Ozturk-Isik
This lecture focuses on Confidence Intervals (CIs), moving beyond simple hypothesis testing to estimate the size and reliability of a treatment effect. While p values tell us…
